TARGETED DELIVERY OF OXALIPLATIN VIA FOLATE-DECORATED NIOSOMAL NANOPARTICLES POTENTIATES RESISTANCE REVERSION OF COLON CANCER CELLS

Targeted delivery of oxaliplatin via folate-decorated niosomal nanoparticles potentiates resistance reversion of colon cancer cells

Background: Colorectal cancer (CRC) is a prevalent type of cancer, ranking third in incidence and fourth in cancer-related deaths globally.The increase in mortality rates related to colorectal cancer among younger patients is a cause for concern.Chemotherapy is the primary approach for palliative care in colon cancer, but the development of drug re

read more



Practical and ethical complexities of MAiD: Examples from Quebec [version 2; peer review: 2 approved, 1 approved with reservations]

Background: Legally practiced assisted dying is an ethically complex area in need of empirical and conceptual work.International research suggests that providing assisted dying may be experienced as rewarding and meaningful but also emotionally and psychologically taxing, associated with feelings of loss and loneliness.Yet little research has been

read more